… Author links open overlay panel Rajiv Jalan 1 , Pere Gines 2 , Jody C Olson 3 , Rajeshwar P
Mookerjee 1 , Richard Moreau 4 , Guadalupe Garcia-Tsao 5 , … Inflammation and infection (R) …

Ammonia is diffused and transported across all plasma membranes. This entails that
hyperammonemia leads to an increase in ammonia in all organs and tissues. It is known that the …

Portal hypertension has traditionally been viewed as a progressive process, involving
ultrastructural changes including fibrosis, nodule formation, and vascular thrombosis, leading to …

The natural history of cirrhosis is characterised by an asymptomatic compensated phase
followed by a decompensated phase, marked by the development of overt clinical signs, the …

Bacterial infections are very common and represent one of the most important reasons of
progression of liver failure, development of liver-related complications, and mortality in patients …

… R. Jalan received research funding from Vital Therapies, has served on the Scientific
Advisory Board for Conatus Pharma, received lecture fees from Gambro, has on-going research …

Acute‐on‐chronic liver failure (ACLF) is characterized by acute decompensation (AD) of
cirrhosis, organ failure(s), and high 28‐day mortality. We investigated whether assessments of …

Acute‐on‐chronic liver failure (ACLF) in cirrhosis is characterized by acute decompensation
(AD), organ failure(s), and high short‐term mortality. Recently, we have proposed (systemic …

Background & Aims Acute decompensation (AD) of cirrhosis is defined as the acute
development of ascites, gastrointestinal hemorrhage, hepatic encephalopathy, infection or any …

Background & Aims There is no histologic classification system to determine prognoses of
patients with alcoholic hepatitis (AH). We identified histologic features associated with disease …