The Genome Sequence of Drosophila melanogaster

…, PG Amanatides, SE Scherer, PW Li, RA Hoskins… - Science, 2000 - science.org
The fly Drosophila melanogaster is one of the most intensively studied organisms in biology
and serves as a model system for the investigation of many developmental and cellular …

Comparative genomics of the eukaryotes

…, F Gong, P Guan, NL Harris, BA Hay, RA Hoskins… - Science, 2000 - science.org
A comparative analysis of the genomes ofDrosophila melanogaster, Caenorhabditis
elegans, and Saccharomyces cerevisiae—and the proteins they are predicted to encode—was …

[HTML][HTML] Current practices in spatial analysis of cancer data: mapping health statistics to inform policymakers and the public

BS Bell, RE Hoskins, LW Pickle… - International journal of …, 2006 - Springer
Background To communicate population-based cancer statistics, cancer researchers have a
long tradition of presenting data in a spatial representation, or map. Historically, health data …

[HTML][HTML] Evolution of genes and genomes on the Drosophila phylogeny

…, LD Hillier, AS Hinrichs, I Holmes, RA Hoskins… - Nature, 2007 - hal.science
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

The developmental transcriptome of Drosophila melanogaster

…, MR Brent, P Cherbas, TR Gingeras, RA Hoskins… - Nature, 2011 - nature.com
Drosophila melanogaster is one of the most well studied genetic model organisms; nonetheless,
its genome still contains unannotated coding and non-coding genes, transcripts, exons …

Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

…, SCR Elgin, TR Gingeras, R Grossman, RA Hoskins… - Science, 2010 - science.org
To gain insight into how genomic information is translated into cellular and developmental
programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) …

The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes

…, PR Hiesinger, KL Schulze, GM Rubin, RA Hoskins… - Genetics, 2004 - academic.oup.com
The Berkeley Drosophila Genome Project (BDGP) strives to disrupt each Drosophila gene
by the insertion of a single transposable element. As part of this effort, transposons in >30,000 …

P[acman]: A BAC Transgenic Platform for Targeted Insertion of Large DNA Fragments in D. melanogaster

KJT Venken, Y He, RA Hoskins, HJ Bellen - Science, 2006 - science.org
We describe a transgenesis platform for Drosophila melanogaster that integrates three recently
developed technologies: a conditionally amplifiable bacterial artificial chromosome (BAC)…

[HTML][HTML] Diversity and dynamics of the Drosophila transcriptome

…, P Carninci, P Cherbas, TR Gingeras, RA Hoskins… - Nature, 2014 - nature.com
Animal transcriptomes are dynamic, with each cell type, tissue and organ system expressing
an ensemble of transcript isoforms that give rise to substantial diversity. Here we have …

MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes

…, JW Carlson, RW Levis, AC Spradling, RA Hoskins… - Nature …, 2011 - nature.com
We demonstrate the versatility of a collection of insertions of the transposon Minos-mediated
integration cassette (MiMIC), in Drosophila melanogaster. MiMIC contains a gene-trap …