Allgrove syndrome (Isolated glucocorticoid deficiency, achalasia and alacrima) was found
in eight members of an inbred French Canadian/North American Indian pedigree. The high …

Introduction: Hypothalamic-pituitary-thyroid axis changes in critical illness result in nonthyroidal
illness syndrome (NTIS) characterized by abnormal TSH and thyroid hormone levels. It is …

In acute illness, cortisol secretion increases whereas that of the adrenal androgens,
dehydroepiandrosterone and dehydroepiandrosterone sulfate declines. The present study …

We studied in vivo and in vitro steroidogenesis in six phenotypic female children with 17-hydroxylase
deficiency. The diagnosis was suspected as a likely cause of familial low renin …

We report on 2 patients who were apparently normal at birth but later developed characteristics
of Wiedemann‐Beckwith syndrome (WBS). Both had hypoglycemia neonatally and …

Kinetic analyses of 17–hydroxylase and 17,20– desmolase activities have been performed
on human adrenal microsomes from 12 individuals, aged 1–60 yr. The median Michaelis …

Alström disease is a rare disorder; less than 20 cases have been reported. An 11-year-old girl
is described with this condition. She has pigmentary retinopathy, sensory neural deafness, …

… Couch, MD … Couch; Screening for Adrenal Antibodies in Children With Type 1 Diabetes and
Autoimmune Thyroid Disease. Diabetes Care 1 November 2003; 26 (11): 3187–3188 …

The kinetics of the inhibitory effects of the imidazole antimicrobial ketoconazole on the activities
of the steroidogenic enzymes distal to cholesterol side-chain cleavage were studied in …

OBJECTIVE To determine the incidence of IDDM among children 0–14 years of age in
Edmonton, Alberta, between 1990 and 1995 by means of a population-based registry. …