TFIID is a large multiprotein complex that initiates assembly of the transcription machinery. It
is unclear how TFIID recognizes promoters in vivo when templates are nucleosome-bound. …

THE β-galactosidase from Escherichia coli was instrumental in the development of the
operon model 1 , and today is one of the most commonly used enzymes in molecular biology. …

Assay validation is a series of the following interrelated processes:-an experimental process:
reagents and protocols are optimised by experimentation to detect the analyte with …

… Ticks were maintained at 98% relative humidity at 4C until used. For determining the
percentage of ticks infected with B. burgdorferi, 50 nymphs (whole bodies) and 20 female ticks (…

… form that included four independent tetramers ~Jacobson & Matthews, 1992!, it was possible
to determine the three-dimensional structure of b-galactosidase ~Jacobson et al., 1994!. …

Background. Gliotoxin is a epipolythiodioxopiperazine toxin that is made by the filamentous
fungus Aspergillus fumigatus. Gliotoxin has a wide range of effects on metazoan cells in …

Eukaryotic cells are thought to contain a single TATA-binding protein (TBP) that directs
transcription by cellular RNA polymerases. Here we report a cell type–specific TBP-related factor (…

Sixteen specific-pathogen-free beagles were infected with Borrelia burgdorferi. Three groups
of 4 dogs were treated with antibiotics for 30 consecutive days starting 120 days after tick …

Seven specific-pathogen-free (SPF) ponies, 1–5 years old, were exposed to Borrelia
burgdorferi–infected adult ticks while being treated with dexamethasone over 5 consecutive days. …

Objective —To evaluate sensitivity and specificity of a new ELISA for antibodies against
Mycobacterium avium subsp paratuberculosis . Design —Cross-sectional observational survey. …