Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
PJ Roberts, CJ Der - Oncogene, 2007 - nature.com
Mitogen-activated protein kinase (MAPK) cascades are key signaling pathways involved in
the regulation of normal cell proliferation, survival and differentiation. Aberrant regulation of …
the regulation of normal cell proliferation, survival and differentiation. Aberrant regulation of …
[HTML][HTML] The Safety Attitudes Questionnaire: psychometric properties, benchmarking data, and emerging research
…, K Rowan, K Vella, J Boyden, PR Roberts… - BMC health services …, 2006 - Springer
Background There is widespread interest in measuring healthcare provider attitudes about
issues relevant to patient safety (often called safety climate or safety culture). Here we report …
issues relevant to patient safety (often called safety climate or safety culture). Here we report …
Reliability and validity in research.
P Roberts, H Priest - Nursing standard, 2006 - go.gale.com
… Specific codes are created to describe the data, such as statements from interview
transcripts, and can be confirmed by revisiting previously coded data periodically to check for …
transcripts, and can be confirmed by revisiting previously coded data periodically to check for …
Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants
…, PC Roberts, J Russell, E Sindall, J Albert, P Kunwar… - Science, 2021 - science.org
… Antibodies that bound to S-2P and RBD of the WA1, B.1.1.7, B.1.351, and P.1 sequences
were detected in all subjects at all time points. Likewise, binding to full-length cell surface–…
were detected in all subjects at all time points. Likewise, binding to full-length cell surface–…
Single-mode photonic band gap guidance of light in air
…, JC Knight, TA Birks, PSJ Russell, PJ Roberts… - science, 1999 - science.org
The confinement of light within a hollow core (a large air hole) in a silica-air photonic crystal
fiber is demonstrated. Only certain wavelength bands are confined and guided down the …
fiber is demonstrated. Only certain wavelength bands are confined and guided down the …
[HTML][HTML] An mRNA vaccine against SARS-CoV-2—preliminary report
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged
in late 2019 and spread globally, prompting an international effort to accelerate development …
in late 2019 and spread globally, prompting an international effort to accelerate development …
[HTML][HTML] Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
…, B Eisenberg, PJ Roberts… - … England Journal of …, 2002 - Mass Medical Soc
Background Constitutive activation of KIT receptor tyrosine kinase is critical in the pathogenesis
of gastrointestinal stromal tumors. Imatinib mesylate, a selective tyrosine kinase inhibitor, …
of gastrointestinal stromal tumors. Imatinib mesylate, a selective tyrosine kinase inhibitor, …
Corporate reputation and sustained superior financial performance
PW Roberts, GR Dowling - Strategic management journal, 2002 - Wiley Online Library
Good corporate reputations are critical because of their potential for value creation, but also
because their intangible character makes replication by competing firms considerably more …
because their intangible character makes replication by competing firms considerably more …
Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
…, B Kiese, B Eisenberg, PJ Roberts… - Journal of clinical …, 2023 - ingentaconnect.com
… A step-wise regression procedure was conducted to retain those variables with a P < .1." …
KIT isoform (P < .0001) or were without a detectable mutation in KIT or PDGFRA (P < .0001). …
KIT isoform (P < .0001) or were without a detectable mutation in KIT or PDGFRA (P < .0001). …
[HTML][HTML] Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
H Joensuu, PJ Roberts… - … England Journal of …, 2001 - Mass Medical Soc
Gastrointestinal stromal tumors are a group of mesenchymal neoplasms that arise from
precursors of the connective-tissue cells of the gastrointestinal tract. They occur predominantly in …
precursors of the connective-tissue cells of the gastrointestinal tract. They occur predominantly in …