The formulation and delivery of biopharmaceutical drugs, such as monoclonal antibodies
and recombinant proteins, poses substantial challenges owing to their large size and …

Although numerous protein therapeutics have been approved or are in advanced clinical
testing, the development of more sophisticated delivery systems for this rapidly expanding …

Purpose Approximately 35% to 60% of all patients with head and neck cancer are malnourished
at the time of their diagnosis because of tumor burden and obstruction of intake or the …

Barron ( 1997 ) and Helson ( 1990 ) independently have suggested that a central element in
all forms of creativity is the desire or goal to be creative, implying creativity as a core value. …

Objective To determine whether the frequency rate of hyperglycemia and infectious
complications can be reduced by an underfeeding strategy in patients requiring total …

… Tumors were cut into 10-μm sections onto Fisher superplus slides (Fisher, Pittsburgh, PA),
air-… Burke PA, DeNardo SJ Antiangiogenic agents and their promising potential for combined …

Despite recent progress, systemic delivery remains the major hurdle for development of safe
and effective small inhibitory RNA (siRNA)–based therapeutics. Encapsulation of siRNA …

PURPOSE: To retrospectively evaluate multi–detector row computed tomography (CT) without
oral contrast material for depiction of bowel and mesenteric injuries that require surgical …

Objectives: To see if selected clinical factors characterize suicides over the age of 60
differently from younger suicides and to ascertain if those factors characterize female and male …

Paclitaxel (Taxol), a promoter of microtubule polymerization and a radiosensitizing agent, is
one of the more active anticancer drugs in the current treatment of solid tumors. In this study, …