Diabetic retinopathy is a leading cause of adult vision loss and blindness. Much of the
retinal damage that characterizes the disease results from retinal vascular leakage and …

… Six severely ill patients received the CCR5 inhibitor leronlimab (PRO 140, CytoDyn) on a
compassionate-use basis, and 2 received the interleukin-6 receptor antagonist tocilizumab …

Background Somatic mutations have the potential to encode “non-self” immunogenic antigens.
We hypothesized that tumors with a large number of somatic mutations due to mismatch-…

… m of the Dome C core (3,060–3,270 m), we extend the existing CO 2 records by two complete
glacial cycles. The data set of the depth interval 3,060–3,190 m, … averages 0.55 m resulting …

We present cosmological parameter results from the final full-mission Planck measurements
of the cosmic microwave background (CMB) anisotropies, combining information from the …

… From experience with other hypophysiotropic and brain peptides 3–5 , and studies suggesting
that CRF could act centrally to activate the sympathetic nervous system (M. Brown et al., in …

A MAJOR problem in the search for new antidepressant drugs is the lack of animal models
which both resemble depressive illness and are selectively sensitive to clinically effective …

THE disease non-insulin-dependent (type 2) diabetes mellitus (NIDDM) is characterized by
abnormally high blood glucose resulting from a relative deficiency of insulin 1 . It affects …

We report on a search for particle dark matter with the XENON100 experiment, operated at
the Laboratori Nazionali del Gran Sasso for 13 months during 2011 and 2012. XENON100 …

… USA), 10 mm of Tris-HCl, 50 mm of KCl, 2.5 mm of MgCl 2 , 0.2 mm of each dNTP, 0.2 μm of
each group-specific primer designed in this study (Table 1), 4 μm of human blocking primers …