… where m is the number of terms in the basis, pi(x) are monomial basis functions, and ai …
where h is the window size, k is the polynomial degree of the basis, m is the order of the …

Background: There is a need for better standardization of the dermoscopic terminology in
assessing pigmented skin lesions. Objective: The virtual Consensus Net Meeting on …

The joint evaluated fission and fusion nuclear data library 3.3 is described. New evaluations
for neutron-induced interactions with the major actinides\(^{235}\hbox {U}\),\(^{238}\hbox {U}\…

Background Enzalutamide (formerly called MDV3100) targets multiple steps in the androgen-receptor–signaling
pathway, the major driver of prostate-cancer growth. We aimed to …

Background Patients with metastatic urothelial carcinoma have few treatment options after
failure of platinum-based chemotherapy. In this trial, we assessed treatment with atezolizumab…

… Twenty microlitres of 1 M HClO 4 was added and this solution was extracted with 11.75/13.25
(v/… We thank M. Liu for technical assistance. REG is supported by funding from the National …

We describe the cloning of p63, a gene at chromosome 3q27–29 that bears strong homology
to the tumor suppressor p53 and to the related gene, p73. p63 was detected in a variety of …

… This cleavage was specific with a catalytic efficiency (k cat /K m , where K m is the Michaelis
constant) of 1.4 × 10 7 M −1 s −1 (K m = 0.6 ± 0.1 μM; k cat = 8.6 ± 0.3 s −1 ) (15) and was …

Defects in iron absorption and utilization lead to iron deficiency and overload disorders.
Adult mammals absorb iron through the duodenum, whereas embryos obtain iron through …

MicroRNAs are abundant in animal genomes and have been predicted to have important roles
in a broad range of gene expression programmes 1 , 2 . Despite this prominence, there is …