User profiles for M. Alison

Alison M Dunning

Centre for Cancer Genetic Epidemiology, Dept of Oncology, University of Cambridge
Verified email at medschl.cam.ac.uk
Cited by 56176

CD133: molecule of the moment

D Mizrak, M Brittan, MR Alison - … of Pathology: A Journal of the …, 2008 - Wiley Online Library
CD133 (prominin‐1) was the first in a class of novel pentaspan membrane proteins to be
identified in both humans and mice, and was originally classified as a marker of primitive …

An introduction to stem cells

MR Alison, R Poulsom, S Forbes… - The Journal of …, 2002 - Wiley Online Library
1998 saw the publication of two papers describing the growth in vitro of human embryonic
stem (ES) cells derived either from the inner cell mass (ICM) of the early blastocyst or the …

Cancer stem cells: problems for therapy?

MR Alison, SML Lim, LJ Nicholson - The Journal of pathology, 2011 - Wiley Online Library
Many, if not all, tumours contain a sub‐population of self‐renewing and expanding stem
cells known as cancer stem cells (CSCs). The symmetric division of CSCs is one mechanism …

Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure

…, A Benigni, N Perico, M Alison… - Journal of the …, 2004 - journals.lww.com
ABSTRACT. Injury to a target organ can be sensed by bone marrow stem cells that migrate
to the site of damage, undergo differentiation, and promote structural and functional repair. …

[HTML][HTML] Hepatocytes from non-hepatic adult stem cells

MR Alison, R Poulsom, R Jeffery, AP Dhillon, A Quaglia… - Nature, 2000 - nature.com
Stem cells are undifferentiated long-lived cells that are capable of many rounds of division.
Here we show that adult human liver cells can be derived from stem cells originating in the …

Rare and low-frequency coding variants alter human adult height

…, LS Adair, DS Alam, E Albrecht, KH Allin, M Allison… - Nature, 2017 - nature.com
Height is a highly heritable, classic polygenic trait with approximately 700 common associated
variants identified through genome-wide association studies so far. Here, we report 83 …

Bone marrow contributes to renal parenchymal turnover and regeneration

…, R Jeffery, T Hunt, M Alison… - The Journal of …, 2001 - Wiley Online Library
… Sections were incubated in 1 M sodium thiocyanate for 10 min at 80C, washed in PBS, and
then digested in 0.4% w/v pepsin in 0.1 M HCl for 10 min at 37C. The reaction was quenched …

Duration of lactation and risk factors for maternal cardiovascular disease

…, RM Ray, AM Stuebe, MA Allison… - Obstetrics & …, 2009 - journals.lww.com
OBJECTIVE: To examine dose–response relationships between the cumulative number of
months women lactated and postmenopausal risk factors for cardiovascular disease. …

A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis

…, V Rey, P Burra, M Rugge, NA Wright, MR Alison - Gastroenterology, 2004 - Elsevier
Background & aims: Myofibroblasts of bone marrow origin have recently been found in a
number of parenchymal organs such as the gut and kidney. We have analyzed the origin of …

The bone marrow functionally contributes to liver fibrosis

FP Russo, MR Alison, BW Bigger, E Amofah, A Florou… - Gastroenterology, 2006 - Elsevier
Background & Aims Bone marrow (BM) cells may transdifferentiate into or fuse with organ
parenchymal cells. BM therapy shows promise in murine models of cirrhosis, and clinical trials …