Conspectus Mesoporous silica nanoparticles (MSNs) are delivery vehicles that can carry
cargo molecules and release them on command. The particles used in the applications …

Francisella tularensis is an intracellular pathogen that survives and multiplies within host
mononuclear phagocytes. We have shown that uptake of the bacterium by human …

We have used the cryosection immunogold technique to study the composition of the
Mycobacterium tuberculosis phagosome. We have used quantitative immunogold staining to …

… pneumophila is reduced by 100-fold (MA Horwitz, unpublished data). Therefore, one-way
by which inhibition of phagosome-lysosome fusion may enhance L. pneumophila survival in …

… Horwitz, MA Phagocytosis of the Legionnaires' disease bacterium (Legionella pneunzophila…
Nash, TW, DM Libby, and MA Horwitz. 1982. Legionnaires' disease bacteria multiply in …

… Horwitz is the recipient of US Public Health Service postdoctoral fellowship AI 05629. …
Horwitz on methodology during a visit to the Center for Disease Control.We thank Dr. Zanvil …

We have examined the receptor-ligand interactions and the method of phagocytosis of virulent
Mycobacterium tuberculosis by human monocytes. mAb against complement receptors (…

Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, is the
world's leading cause of death in humans from a single infectious agent. A safe and effective …

Tuberculosis (TB) continues to ravage humanity, causing 2 million deaths per year. A vaccine
against TB more potent than the current live vaccine, bacillus Calmette–Guérin (BCG), is …

Francisella tularensisis subsp. tularensis is an intracellular bacterial pathogen and the causative
agent of the life-threatening zoonotic disease tularemia. The Francisella Pathogenicity …