User profiles for E. D. Mann

Ed Mann

Asscociate Professor of Neuroscience, Oxford University
Verified email at dpag.ox.ac.uk
Cited by 4856

[HTML][HTML] Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model

L Verret, EO Mann, GB Hang, AMI Barth, I Cobos, K Ho… - Cell, 2012 - cell.com
Alzheimer's disease (AD) results in cognitive decline and altered network activity, but the
mechanisms are unknown. We studied human amyloid precursor protein (hAPP) transgenic …

[PDF][PDF] Perisomatic feedback inhibition underlies cholinergically induced fast network oscillations in the rat hippocampus in vitro

EO Mann, JM Suckling, N Hajos, SA Greenfield… - Neuron, 2005 - cell.com
Gamma frequency network oscillations are assumed to be important in cognitive processes,
including hippocampal memory operations, but the precise functions of these oscillations …

Role of GABAergic inhibition in hippocampal network oscillations

EO Mann, O Paulsen - Trends in neurosciences, 2007 - cell.com
Physiological rhythmic activity in cortical circuits relies on GABAergic inhibition to balance
excitation and control spike timing. With a focus on recent experimental progress in the …

Parvalbumin and somatostatin interneurons contribute to the generation of hippocampal gamma oscillations

…, YL Tan, G Kontou, AL Upton, EO Mann - Journal of …, 2020 - Soc Neuroscience
γ-frequency oscillations (30-120 Hz) in cortical networks influence neuronal encoding and
information transfer, and are disrupted in multiple brain disorders. While synaptic inhibition is …

Which GABAA receptor subunits are necessary for tonic inhibition in the hippocampus?

J Glykys, EO Mann, I Mody - Journal of Neuroscience, 2008 - Soc Neuroscience
GABA A receptors (GABA A Rs) assembled of different subunits mediate tonic and phasic
inhibition in hippocampal neurons. CA1/CA3 pyramidal cells (PCs) predominantly express α5 …

Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro

N Hájos, J Pálhalmi, EO Mann, B Németh… - Journal of …, 2004 - Soc Neuroscience
Gamma frequency (30-100 Hz) network oscillations occur in the intact hippocampus during
awake, attentive behavior. Here, we explored the underlying cellular mechanisms in an in …

Control of hippocampal gamma oscillation frequency by tonic inhibition and excitation of interneurons

EO Mann, I Mody - Nature neuroscience, 2010 - nature.com
Gamma-frequency oscillations depend on phasic synaptic GABA A receptor (GABA A R)-mediated
inhibition to synchronize spike timing. The spillover of synaptically released GABA …

Maintaining network activity in submerged hippocampal slices: importance of oxygen supply

…, TJ Ellender, R Zemankovics, EO Mann… - European Journal of …, 2009 - Wiley Online Library
Studies in brain slices have provided a wealth of data on the basic features of neurons and
synapses. In the intact brain, these properties may be strongly influenced by ongoing network …

Distinct roles of GABAA and GABAB receptors in balancing and terminating persistent cortical activity

EO Mann, MM Kohl, O Paulsen - Journal of Neuroscience, 2009 - Soc Neuroscience
Cortical networks spontaneously fluctuate between persistently active Up states and quiescent
Down states. The Up states are maintained by recurrent excitation within local circuits, …

Prevalence of Salmonella and thermophilic Campylobacter in fresh pork, beef, veal and poultry in Canada

AM Lammerding, MM Garcia, ED Mann… - Journal of Food …, 1988 - Elsevier
A national surveillance program was undertaken in Canada to establish the prevalence and
distribution of Salmonella and thermophilic Campylobacter biotypes in slaughter animals …