User profiles for E. D. Mann
Ed MannAsscociate Professor of Neuroscience, Oxford University Verified email at dpag.ox.ac.uk Cited by 4856 |
[HTML][HTML] Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model
Alzheimer's disease (AD) results in cognitive decline and altered network activity, but the
mechanisms are unknown. We studied human amyloid precursor protein (hAPP) transgenic …
mechanisms are unknown. We studied human amyloid precursor protein (hAPP) transgenic …
[PDF][PDF] Perisomatic feedback inhibition underlies cholinergically induced fast network oscillations in the rat hippocampus in vitro
EO Mann, JM Suckling, N Hajos, SA Greenfield… - Neuron, 2005 - cell.com
Gamma frequency network oscillations are assumed to be important in cognitive processes,
including hippocampal memory operations, but the precise functions of these oscillations …
including hippocampal memory operations, but the precise functions of these oscillations …
Role of GABAergic inhibition in hippocampal network oscillations
Physiological rhythmic activity in cortical circuits relies on GABAergic inhibition to balance
excitation and control spike timing. With a focus on recent experimental progress in the …
excitation and control spike timing. With a focus on recent experimental progress in the …
Parvalbumin and somatostatin interneurons contribute to the generation of hippocampal gamma oscillations
γ-frequency oscillations (30-120 Hz) in cortical networks influence neuronal encoding and
information transfer, and are disrupted in multiple brain disorders. While synaptic inhibition is …
information transfer, and are disrupted in multiple brain disorders. While synaptic inhibition is …
Which GABAA receptor subunits are necessary for tonic inhibition in the hippocampus?
GABA A receptors (GABA A Rs) assembled of different subunits mediate tonic and phasic
inhibition in hippocampal neurons. CA1/CA3 pyramidal cells (PCs) predominantly express α5 …
inhibition in hippocampal neurons. CA1/CA3 pyramidal cells (PCs) predominantly express α5 …
Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro
N Hájos, J Pálhalmi, EO Mann, B Németh… - Journal of …, 2004 - Soc Neuroscience
Gamma frequency (30-100 Hz) network oscillations occur in the intact hippocampus during
awake, attentive behavior. Here, we explored the underlying cellular mechanisms in an in …
awake, attentive behavior. Here, we explored the underlying cellular mechanisms in an in …
Control of hippocampal gamma oscillation frequency by tonic inhibition and excitation of interneurons
Gamma-frequency oscillations depend on phasic synaptic GABA A receptor (GABA A R)-mediated
inhibition to synchronize spike timing. The spillover of synaptically released GABA …
inhibition to synchronize spike timing. The spillover of synaptically released GABA …
Maintaining network activity in submerged hippocampal slices: importance of oxygen supply
…, TJ Ellender, R Zemankovics, EO Mann… - European Journal of …, 2009 - Wiley Online Library
Studies in brain slices have provided a wealth of data on the basic features of neurons and
synapses. In the intact brain, these properties may be strongly influenced by ongoing network …
synapses. In the intact brain, these properties may be strongly influenced by ongoing network …
Distinct roles of GABAA and GABAB receptors in balancing and terminating persistent cortical activity
Cortical networks spontaneously fluctuate between persistently active Up states and quiescent
Down states. The Up states are maintained by recurrent excitation within local circuits, …
Down states. The Up states are maintained by recurrent excitation within local circuits, …
Prevalence of Salmonella and thermophilic Campylobacter in fresh pork, beef, veal and poultry in Canada
AM Lammerding, MM Garcia, ED Mann… - Journal of Food …, 1988 - Elsevier
A national surveillance program was undertaken in Canada to establish the prevalence and
distribution of Salmonella and thermophilic Campylobacter biotypes in slaughter animals …
distribution of Salmonella and thermophilic Campylobacter biotypes in slaughter animals …