… With a set of conditions for the polycyclization based on the use of excess triflic acid (Conditions
A) or catalytic bistriflimide (Conditions B), we next evaluated the generality of our …

… Sandrine Py on the chemistry of nitrones and obtained his B.Sc. degree the same year. …
to other classes of electron-deficient ynamines and b) the lack of reactivity of acyclic secondary …

… ion intermediates such as ion B 1 , with an upper face being … be postulated that an intermediate
ion B 2 could be formed … of the keteniminium ion B 3 through a hyperconjugation effect …

… Whereas the allylic substituted benzenesulfonamide A showed only a micromolar level of
inhibition toward hCA IX, its fluorinated analogue B inhibited hCA IX at the nanomolar level, …

Objectives Osteoarthritis is a painful joint disease responsible for walking impairment. Its
quantitative assessment by gait analysis in mice may be a relevant and noninvasive strategy to …

Periprosthetic joint infections (PJI) occur in 0.5 to 2.8% of total knee arthroplasties (TKA)
and expose them to an increase of morbidity and mortality. TKA are mainly performed after …

Polycyclization reactions are among the most efficient synthetic tools for the synthesis of
complex, polycyclic molecules in a single operation from simple starting materials. We report in …

… Acetanilide 1 b yielded products 2 b X in good yields using an excess of NaX. Gratifyingly,
4-halogeno acetanilides 1 c–1 e were selectively chlorinated and iodinated in position 3. …

Purpose Jumper’s knee is characterized by an anterior knee pain during tendon palpation
and can be classified in overuse pathologies, secondary to repetitive jumps. The prevalence …

… Melting points were determined in a capillary tube with a device Büchi melting point B-545 …
mmol) following the general procedures A then B. The reaction crude was purified over silica …