[HTML][HTML] Fluorescein derivatives as fluorescent probes for pH monitoring along recent biological applications

F Le Guern, V Mussard, A Gaucher, M Rottman… - International Journal of …, 2020 - mdpi.com
Potential of hydrogen (pH) is one of the most relevant parameters characterizing aqueous
solutions. In biology, pH is intrinsically linked to cellular life since all metabolic pathways are …

[HTML][HTML] Spondylodiscitis due to Propionibacterium acnes: report of twenty-nine cases and a review of the literature

…, L Vauthey, N Asseray, N Passuti, M Rottman… - Clinical Microbiology …, 2010 - Elsevier
Propionibacterium acnes is the most frequent anaerobic pathogen found in spondylodiscitis.
A documented case required microbiological proof of P. acnes with clinical and radiological …

Spiroindolones, a potent compound class for the treatment of malaria

M Rottmann, C McNamara, BKS Yeung, MCS Lee… - science, 2010 - science.org
Recent reports of increased tolerance to artemisinin derivatives—the most recently adopted
class of antimalarials—have prompted a need for new treatments. The spirotetrahydro-β-…

Antimicrobial activity of mucosal-associated invariant T cells

…, L Duban, D Robert, S Huang, M Rottman… - Nature …, 2010 - nature.com
… We next examined the role of MAIT cells in a mycobacterium infection model using M.
abscessus 28 . M. abscessus– infected BMDCs strongly stimulated mouse MAIT cells in a dose- …

[HTML][HTML] Non Mycobacterial Virulence Genes in the Genome of the Emerging Pathogen Mycobacterium abscessus

…, C Schenowitz, C Dossat, V Barbe, M Rottman… - PloS one, 2009 - journals.plos.org
… Many of the “non mycobacterial” factors detected in M. abscessus are also present in two of
… This study elucidates the genetic basis of the unique pathogenicity of M. abscessus among …

An extracorporeal blood-cleansing device for sepsis therapy

…, H Tobin, MJ Cartwright, AL Watters, M Rottman… - Nature medicine, 2014 - nature.com
Here we describe a blood-cleansing device for sepsis therapy inspired by the spleen, which
can continuously remove pathogens and toxins from blood without first identifying the …

Multicenter study of prevalence of nontuberculous mycobacteria in patients with cystic fibrosis in France

…, V Vincent, B Fauroux, M Rottman… - Journal of clinical …, 2009 - Am Soc Microbiol
… abscessus sensu lato, or the MABSC) was shown to include at least three distinct species, M.
… We also show that the proportion of cases satisfying the ATS criteria is similar to that for M. …

[HTML][HTML] Eculizumab as an emergency treatment for adult patients with severe COVID-19 in the intensive care unit: a proof-of-concept study

…, AL Roux, A Marchal, H Michelon, M Rottman… - …, 2020 - thelancet.com
Background Complement pathway inhibition may provide benefit for severe acute
respiratory illnesses caused by viral infections such as COVID-19. We present results from a …

Hypervirulence of a Rough Variant of the Mycobacterium abscessus Type Strain

…, C Soudais, JL Gaillard, M Rottman - Infection and …, 2007 - Am Soc Microbiol
We isolated a rough variant of Mycobacterium abscessus CIP 104536T during experimental
infection of mice. We show that this variant has lost the ability to produce glycopeptidolipids, …

Suppression of surgeons' bacterial hand flora during surgical procedures with a new antimicrobial surgical glove

…, K Ouriel, M Suchomel, ML McLaws, M Rottman… - Surgical …, 2014 - liebertpub.com
Background: Perforations of surgical gloves are common and increase with the duration of
glove wear. Skin flora, re-grown after pre-operative disinfection of the hands, may …