Autism spectrum disorder (ASD) is a particularly important risk factor for challenging behaviours
such as aggression, tantrums, self-injury and pica. Adults with ASD have rarely been …

The discovery of cancer dependencies has the potential to inform therapeutic strategies and
to identify putative drug targets. Integrating data from comprehensive genomic profiling of …

Consumption beyond homeostatic needs, referred to here as reward-based feeding behavior,
is a central contributor to the current obesity epidemic worldwide. Importantly, reward-…

Endogenous opioid peptides (EOP) mediate progesterone-negative feedback in many
species, but the specific EOP systems involved remain unresolved. We first addressed this …

Most isolates of human rhinovirus, the common cold virus, replicate more robustly at the cool
temperatures found in the nasal cavity (33–35 C) than at core body temperature (37 C). To …

Structural brain change and concomitant cognitive decline are the seemingly unavoidable
escorts of aging. Despite accumulating studies detailing the effects of age on the brain and …

The uncertain and fast-changing nature of operational environments is driving a growing
interest in systems that display desirable lifecycle properties (ie, ilities). A survivable, flexible, or …

Game-based learning has the potential to improve the education and performance of engineers
and decision makers in the systems engineering field. This paper reviews the arguments …

This study examined age-related changes in swallowing from an integrated biomechanical
and functional imaging perspective in order to more comprehensively characterize changes …

Diffuse petechiae, gravity-dependent, and multiple, generalized palpable purpura, and
acroischemia (primarily finger/toe cyanosis, but neither skin bulla nor dry gangrene) were seen in …