… The M 1 and M 2 PKs are the product of the mutually exclusive alternate splicing of the
same mRNA generated from PK-M, 14 whereas L and R PKs are both encoded by the PK-LR …

… Among LPS alterations, the cationic substitution of phosphate groups by the addition of 4-amino-4-deoxy-L-arabinose
(L-Ara4N), decreases the net negative charge of lipid A. B. …

Nontuberculous mycobacteria (NTM) have recently emerged as important pathogens among
cystic fibrosis (CF) patients worldwide. Mycobacterium abscessus is becoming the most …

Pyruvate kinase (PK) is critical for the regulation of the glycolytic pathway. The regulatory
properties ofEscherichia coli were investigated by mutating six charged residues involved in …

In living organisms, genes encoding proteins that contain flavins as a prosthetic group constitute
approximately 2–3% of the total. The fluorescence of flavin cofactors in these proteins is …

… Keri for providing inhibitors; L. Menin for technical assistance with mass spectrometry; A. …
Keri for providing inhibitors; L. Menin for technical assistance with mass spectrometry; A. Liav …

Deficiency of human erythrocyte isozyme (RPK) is, together with glucose-6-phosphate
dehydrogenase deficiency, the most common cause of the nonspherocytic hemolytic anemia. To …

Phenotypic screening of a quinoxaline library against replicating Mycobacterium
tuberculosis led to the identification of lead compound Ty38c (3-((4-methoxybenzyl)amino)-6-(…

The re-emergence of tuberculosis in recent years led the World Health Organization (WHO)
to launch the Stop TB Strategy program. Beside repurposing the existing drugs and …

… The recombinant enzyme showed a strong preference for l-asparagine over l-glutamine
and, in contrast to most l-asparaginases, it exhibited a sigmoidal behaviour towards l-glutamine. …