MUC1 is a high molecular weight glycoprotein that is overexpressed in breast cancer. Aberrant
O-linked glycosylation of MUC1 in cancer has been implicated in disease progression. …

BACKGROUND. Triple‐negative breast cancer (estrogen receptor‐negative, progesterone
receptor‐negative, and HER2‐negative) is a high risk breast cancer that lacks the benefit of …

Purpose Over 1 billion doses of COVID-19 vaccines have been already administered
across the United States, the United Kingdom and the European Union at the time of writing. …

Breast cancer models of acquired tamoxifen resistance, oestrogen receptor (ER) + /ER − de
novo resistance and gene transfer studies cumulatively demonstrate the increased …

We have conducted a clinical trial of a novel pure antiestrogen, 7α-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]estra-1,3,5,(10)-triene-3,17β-diol
(ICI 182780), to assess its tolerance, …

… John FR Robertson, Nottingham City Hospital, Nottingham, United Kingdom; John
Sainsbury, Huddersfield Royal Infirmary, Huddersfield, United Kingdom; Alistair M. Thompson, …

Purpose: Previous conflicting results about the prognostic significance of estrogen receptor (ER)-β
in breast cancer may be explained by contribution of isoforms, of which five exist. Our …

BACKGROUND: Breast cancer is recognised to be a heterogeneous disease with a range
of morphological appearances and behaviours. The recently recognised basal phenotype (BP…

Aberrant glycosylation on glycoproteins that are either presented on the surface or secreted
by cancer cells is a potential source of disease biomarkers and provides insights into …

The aim of this study was to assess the morphological characteristics and immunohistochemical
profile of breast carcinomas with basal and myoepithelial phenotypes to obtain a better …